Both Familial Parkinson's Disease Mutations Accelerate α-Synuclein Aggregation

Linda O. Narhi, Stephen Wood, Shirley Steavenson, +11

Journal of Biological Chemistry

Parkinson's Disease-associated α-Synuclein Is More Fibrillogenic than β- and γ-Synuclein and Cannot Cross-seed Its Homologs

Anja Leona Biere, Stephen Wood, Jette Wypych, +10

Journal of Biological Chemistry

Qualification of FTIR spectroscopic method for protein secondary structural analysis

Yijia Jiang, Cynthia Li, Xichdao Nguyen, +4

Journal of Pharmaceutical Sciences

Spectroscopic MethodBiochemistryProtein FoldingSpectroscopyFtir Spectroscopic Method +10

Applications of circular dichroism (CD) for structural analysis of proteins: qualification of near‐ and far‐UV CD for protein higher order structural analysis

Cynthia H. Li, Xichdao Nguyen, Linda O. Narhi, +5

Journal of Pharmaceutical Sciences

BiochemistryFar‐uv CdNatural SciencesMolecular BiologyStructural Analysis +4

Applications of Differential Scanning Calorimetry for Thermal Stability Analysis of Proteins: Qualification of DSC

Jie Wen, Kelly K. Arthur, Letha Chemmalil, +3

Journal of Pharmaceutical Sciences

EngineeringDerivative ThermogravimetryBiochemistryDifferential Scanning CalorimetryProtein Folding +9

Tungsten-induced protein aggregation: Solution behavior

Yijia Jiang, Yasser Nashed-Samuel, Cynthia Li, +14

Journal of Pharmaceutical Sciences

Physicochemical AnalysisProtein FoldingTungsten-induced Protein AggregationMolecular AggregateMedicine +1

Root Cause Analysis of Tungsten-Induced Protein Aggregation in Pre-filled Syringes.

Wei Liu, R. M. Swift, Gianni Torraca, +8

PubMed

Root Cause AnalysisChemical EngineeringResidual TungstenResidual Tungsten ContentEngineering +11

Physical and biophysical effects of polysorbate 20 and 80 on darbepoetin alfa

Songpon Deechongkit, Jie Wen, Linda O. Narhi, +4

Journal of Pharmaceutical Sciences

Darbepoetin AlfaBotanyBiophysical EffectsPolysorbate 20Pharmacology

Precision of protein aggregation measurements by sedimentation velocity analytical ultracentrifugation in biopharmaceutical applications

John P. Gabrielson, Kelly K. Arthur, Michael R. Stoner, +8

Analytical Biochemistry

EngineeringBiochemistryNatural SciencesBioanalysisMass Spectrometry +13

Comparison of quantitative spectral similarity analysis methods for protein higher-order structure confirmation

Brandon M. Teska, Cynthia Li, Bradley C. Winn, +3

Analytical Biochemistry

BiochemistryStructural BioinformaticsProtein FoldingMedicineNatural Sciences +9