Jack Liang

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 601 citations

Enzyme-catalyzed Reactions, Biomanufacturing, Biosynthesis +15

Development of a Biocatalytic Process as an Alternative to the (−)-DIP-Cl-Mediated Asymmetric Reduction of a Key Intermediate of Montelukast

Jack Liang, James Lalonde, Birthe Borup et al. · Organic Process Research & Development · 2009 · 223 citations

Key Intermediate, Engineering, Asymmetric Reduction +19

Efficient, Chemoenzymatic Process for Manufacture of the Boceprevir Bicyclic [3.1.0]Proline Intermediate Based on Amine Oxidase-Catalyzed Desymmetrization

Tao Li, Jack Liang, Alexandre Ambrogelly et al. · Journal of the American Chemical Society · 2012 · 210 citations

Bioorganic Chemistry, New Drug Treatment, Organic Chemistry +21

Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas

Oscar Alvizo, Luan J. Nguyen, Christopher K. Savile et al. · Proceedings of the National Academy of Sciences · 2014 · 190 citations · Full text

Dynamic Kinetic Resolutions Catalyzed by a Planar-Chiral Derivative of DMAP:  Enantioselective Synthesis of Protected α-Amino Acids from Racemic Azlactones

Jack Liang, J. Craig Ruble, Gregory C. Fu · The Journal of Organic Chemistry · 1998 · 157 citations

Protected α-Amino Acids, Engineering, Biochemistry +13