Lawrence J. Heinz

Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F

Liandong Ma, Joshua R. Clayton, Richard A. Walgren et al. · Blood Cancer Journal · 2013 · 64 citations · Full text

Synthesis and structure-activity relationships of benzophenones as inhibitors of cathepsin D

Celia A. Whitesitt, Richard L. Simon, Jon K. Reel et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 51 citations

Medicinal Chemistry, Cathepsin D, Heterocyclic +10

DL-Tetrazol-5-ylglycine, a highly potent NMDA agonist: its synthesis and NMDA receptor efficacy

W. H. W. LUNN, Darryle D. Schoepp, David O. Calligaro et al. · Journal of Medicinal Chemistry · 1992 · 36 citations

Potent Nmda Agonist, Pharmacotherapy, Experimental Pharmacology +18

An Efficient Synthesis of <i>cis</i>- and <i>trans</i>-Methyl-3-hydroxy-2-pyrrolidone- 5-carboxylates, Key Intermediates for the Synthesis of γ-Substituted Glutamic Acid Analogs

Lawrence J. Heinz, W. H. W. LUNN, Robert E. Murff et al. · The Journal of Organic Chemistry · 1996 · 23 citations

Key Intermediates, Diversity Oriented Synthesis, Engineering +12

Heteroatom-substitution as a strategy for increasing the potency of competitive NMDA antagonists

Paul L. Ornstein, M. Brian Arnold, W. H. W. LUNN et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 21 citations

Biochemistry, Medicine, Competitive Nmda Antagonists +8