Debora N Mancini

CpG methylation within the 5′ regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site

Debora N Mancini, David I. Rodenhiser, Peter Ainsworth et al. · Oncogene · 1998 · 191 citations

Life Sciences, Genetics, Molecular Biology +15

Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors

Debora N Mancini, Shiva M Singh, Trevor Archer et al. · Oncogene · 1999 · 130 citations

Life Sciences, Genetics, Molecular Biology +13

Constitutively Methylated Cp G Dinucleotides as Mutation Hot Spots in the Retinoblastoma Gene (RB1)

Debora N Mancini, Shiva M. Singh, Peter Ainsworth et al. · The American Journal of Human Genetics · 1997 · 86 citations · Full text

Medicine, Genetics, Molecular Genetics +13

Homonucleotide tracts, short repeats and CpG/CpNpG motifs are frequent sites for heterogeneous mutations in the Neurofibromatosis type 1 (NF1) tumour-suppressor gene

David I. Rodenhiser, J.D Andrews, Debora N Mancini et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 1997 · 38 citations

Medicine, Genetics, Molecular Genetics +12