Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals

Stefanie Grund, Barbara L. Mui, Michael J. Hope, +3

Molecular Therapy

Lipid NanoparticlesMolecular BiologyGene DeliveryInnate ImmunityTherapeutics +20

The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation

Maria Polycarpou‐Schwarz, Matthias Groß, Pieter Mestdagh, +8

Oncogene

Tumor BiologyCancer-associated Microprotein Casimo1MedicineSqualene EpoxidaseCell Biology +6

The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression

Stefanie Grund, Tamás Fischer, Ghislain G. Cabal, +3

The Journal of Cell Biology

Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river

Steffen Keiter, Stefanie Grund, Bert van Bavel, +8

Analytical and Bioanalytical Chemistry

Organic GeochemistryDanube RiverMedicineToxicologyEnvironmental Toxicology +1

The OECD validation program of the H295R steroidogenesis assay: Phase 3. Final inter-laboratory validation study

Markus Hecker, Henner Hollert, Ralph L. Cooper, +12

Environmental Science and Pollution Research

OxysterolOecd Validation ProgramEndocrine MechanismMedicineBioanalysis +8

Comparison of in vitro and in situ genotoxicity in the Danube River by means of the comet assay and the micronucleus test

Melanie I. Boettcher, Stefanie Grund, Steffen Keiter, +6

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Comet AssayEnvironmental EngineeringMicronucleus TestToxicology TestingToxicology +6

The endocrine disrupting potential of sediments from the Upper Danube River (Germany) as revealed by in vitro bioassays and chemical analysis

Stefanie Grund, Eric Higley, René Schönenberger, +5

Environmental Science and Pollution Research

Endocrine DisruptorsEnvironmental ChemistryEngineeringChemical AnalysisSediment-water Interaction +9

The OECD Validation Program of the H295R Steroidogenesis Assay for the Identification of In Vitro Inhibitors and Inducers of Testosterone and Estradiol Production. Phase 2: Inter-Laboratory Pre-Validation Studies (8 pp)

Markus Hecker, Henner Hollert, Ralph L. Cooper, +14

Environmental Science and Pollution Research

H295r Steroidogenesis AssayOecd Validation ProgramEndocrine MechanismMedicineEstradiol Production +9

Alternative splicing affects the subcellular localization of Drosha

Steffen Link, Stefanie Grund, Sven Diederichs

Nucleic Acids Research

Functional GenomicsDevelopmental BiologyPri-mirna ProcessingDrosha IsoformsNovel Isoforms +11

Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect-directed analysis

Eric Higley, Stefanie Grund, Paul D. Jones, +9

Environmental Toxicology and Chemistry