Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

S. Yamada, Masato Hatta, Bart L. Staker, +23

PLoS Pathogens

Host-adapting Amino AcidVirus StructureStructural CharacterizationViral ReplicationMolecular Virology +12

Increasing the structural coverage of tuberculosis drug targets

Loren Baugh, Isabelle Phan, Darren W. Begley, +32

Tuberculosis

Pulmonary TuberculosisDrug TargetStructural CoverageMedicineTuberculosis Prevention +6

Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome

Loren Baugh, Larry A. Gallagher, Rapatbhorn Patrapuvich, +24

PLoS ONE

Structural genomics of infectious disease drug targets: the SSGCID

Robin Stacy, Darren W. Begley, Isabelle Phan, +6

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Drug TargetSsgcid PipelineStructural BioinformaticsBiomolecular Structure PredictionProtein Folding +13

Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the <i>Plasmodium falciparum</i> Drug Target, Prolyl-tRNA-synthetase

Stephen N. Hewitt, David M. Dranow, Benjamin G. Horst, +23

ACS Infectious Diseases

Structural CharacterizationDrug TargetBioorganic ChemistryAntiparasitic AgentMalaria +16

Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems

Joseph J. Gillespie, Isabelle Phan, Holger Scheib, +12

mBio

Targeted, haplotype-resolved resequencing of long segments of the human genome

Christopher K. Raymond, Sandhya Subramanian, Marcia N. Paddock, +12

Genomics

Haplotype DeterminationGeneticsGenome StructureMolecular BiologyGenome Analysis +5

Wheat germ cell-free expression system as a pathway to improve protein yield and solubility for the SSGCID pipeline

Katherine J. Guild, Yang Zhang, Robin Stacy, +4

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Ssgcid PipelineProtein YieldEngineeringEscherichia ColiCrop Improvement +18

A Structural Biology Approach Enables the Development of Antimicrobials Targeting Bacterial Immunophilins

Darren W. Begley, David Fox, Dominic C. Jenner, +19

Antimicrobial Agents and Chemotherapy

Crystal StructureBacteriophageMolecular BiologyStructural Biology ApproachChemical Biology +16

Structure of nitrilotriacetate monooxygenase component B from<i>Mycobacterium thermoresistibile</i>

Y. Zhang, Thomas E. Edwards, Darren W. Begley, +12

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Pulmonary TuberculosisBiochemistryM. TuberculosisNatural SciencesMycobacterium Tuberculosis +9