Mapping the Main Immunogenic Region and Toxin-Binding Site of the Nicotinic Acetylcholine Receptor

T. Barkas, Alex Mauron, Beat Roth, +3

Science

Monoclonal antibodies to the main immunogenic region of the nicotinic acetylcholine receptor bind to residues 61-76 of the alpha subunit.

T. Barkas, J M Gabriel, Alex Mauron, +5

Journal of Biological Chemistry

ImmunologyImmunodominanceAntigen ProcessingImmunotherapyNicotine +18

Autoimmune T lymphocytes in myasthenia gravis. Determination of target epitopes using T lines and recombinant products of the mouse nicotinic acetylcholine receptor gene.

Arthur Melms, Susanne Chrestel, Berthold Schalke, +4

Journal of Clinical Investigation

HistocompatibilityTarget EpitopesLaboratory ImmunologyImmunologyImmunodominance +15

T cell epitopes in experimental autoimmune myasthenia gravis of the rat: strain‐specific epitopes and cross‐reaction between two distinct segments of the α chain of the nicotinic acetylcholine receptor (torpedo californica)

Yiping Zhang, T. Barkas, Marcel A. Juillerat, +2

European Journal of Immunology

ImmunologyImmune RegulationImmunodominanceImmunologic MechanismAntigen Processing +14

Antigenic sites of the nicotinic acetylcholine receptor cannot be predicted from the hydrophilicity profile

Marcel A. Juillerat, T. Barkas, Socrates J. Tzartos

FEBS Letters

C2 synthesis by human monocytes is modulated by a nicotinic cholinergic receptor

K Whaley, David F. Lappin, T. Barkas

Nature

Signal TransductionMolecular PhysiologyMedicineNicotineNeurotransmitter +8

Immunological heterogeneity of autoreactive T lymphocytes against the nicotinic acetylcholine receptor in myasthenic patients

Y. Zhang, Myriam Schluep, Séverine Frutiger, +4

European Journal of Immunology

Detection of immune complexes in polymyositis

W. M. H. Behan, T. Barkas, P. O. Behan

Acta Neurologica Scandinavica

InflammationAutoimmune DiseaseAllergyImmunodeficienciesImmunology +11

Induction of an Fc conformational change by binding of antigen: the generation of protein A-reactive sites in chicken immunoglobulin.

T. Barkas, C.M. Watson

PubMed

Protein A-reactive SitesImmunologyStaphylococcus AureusAntigen ProcessingImmunoassays +14

Inhibition of antibody-dependent cell-mediated cytotoxicity (ADCC) as a means of detection of immune complexes in the sera of patients with thyroid disorders and bronchogenic carcinoma.

T. Barkas, S F Al-Khateeb, W J Irvine, +2

PubMed

ImmunotoxicologyThyroid DiseaseImmunologyPathologyAntibody-dependent Cell-mediated Cytotoxicity +12