Raymond A. Firestone

Cure of Xenografted Human Carcinomas by BR96-Doxorubicin Immunoconjugates

Pamela A. Trail, David Willner, Shirley J. Lasch et al. · Science · 1993 · 554 citations

Medicine, Oncology, Pharmacology +16

Cathepsin B-Labile Dipeptide Linkers for Lysosomal Release of Doxorubicin from Internalizing Immunoconjugates:  Model Studies of Enzymatic Drug Release and Antigen-Specific In Vitro Anticancer Activity

Gene M. Dubowchik, Raymond A. Firestone, Linda Padilla et al. · Bioconjugate Chemistry · 2002 · 546 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Mechanism of 1,3-dipolar cycloadditions

Raymond A. Firestone · The Journal of Organic Chemistry · 1968 · 294 citations

Natural Sciences, Chemistry, Analytical Chemistry +6

Induction of cell death by the lysosomotropic detergent MSDH

Wei Li, Gunnar Nordgren, Helge Dalen et al. · FEBS Letters · 2000 · 243 citations

Life Sciences, Biochemistry, Cell Biology +15

(6-Maleimidocaproyl)hydrazone of doxorubicin. A new derivative for the preparation of immunoconjugates of doxorubicin

David Willner, Pamela A. Trail, Sandra J. Hofstead et al. · Bioconjugate Chemistry · 1993 · 222 citations

Pharmacy, Biochemistry, Pharmaceutics +17