Sandra J. Hofstead

Cure of Xenografted Human Carcinomas by BR96-Doxorubicin Immunoconjugates

Pamela A. Trail, David Willner, Shirley J. Lasch et al. · Science · 1993 · 554 citations

Medicine, Oncology, Pharmacology +16

Cathepsin B-Labile Dipeptide Linkers for Lysosomal Release of Doxorubicin from Internalizing Immunoconjugates:  Model Studies of Enzymatic Drug Release and Antigen-Specific In Vitro Anticancer Activity

Gene M. Dubowchik, Raymond A. Firestone, Linda Padilla et al. · Bioconjugate Chemistry · 2002 · 546 citations

Pharmacy, Pharmaceutics, Pharmacology +17

(6-Maleimidocaproyl)hydrazone of doxorubicin. A new derivative for the preparation of immunoconjugates of doxorubicin

David Willner, Pamela A. Trail, Sandra J. Hofstead et al. · Bioconjugate Chemistry · 1993 · 222 citations

Pharmacy, Biochemistry, Pharmaceutics +17

Kedarcidin, a new chromoprotein antitumor antibiotic: structure elucidation of kedarcidin chromophore

John E. Leet, Daniel R. Schroeder, Sandra J. Hofstead et al. · Journal of the American Chemical Society · 1992 · 161 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Monoclonal Antibody Conjugates of Doxorubicin Prepared with Branched Peptide Linkers:  Inhibition of Aggregation by Methoxytriethyleneglycol Chains

Dalton King, Gene M. Dubowchik, Harold Mastalerz et al. · Journal of Medicinal Chemistry · 2002 · 138 citations

Pharmacy, Medicinal Chemistry, Pharmaceutics +17