Frank W. Kari

Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice.

Sandra E. Dunn, Frank W. Kari, John E. French et al. · PubMed · 1997 · 440 citations

Nutrition, Chemoprevention Strategy, Pathology +23

Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs.

S E Dunn, R A Hardman, Frank W. Kari et al. · PubMed · 1997 · 204 citations

Breast Oncology, Immunology, Cell Death +18

Green tea increases anti-inflammatory tristetraprolin and decreases pro-inflammatory tumor necrosis factor mRNA levels in rats

Heping Cao, Meghan Kelly, Frank W. Kari et al. · Journal of Inflammation · 2007 · 99 citations · Full text

The growth hormone: insulin-like growth factor 1 axis is a mediator of diet restriction-induced inhibition of mononuclear cell leukemia in Fischer rats.

Stephen D. Hursting, Boyd R. Switzer, John E. French et al. · PubMed · 1993 · 90 citations

Mncl Cell Proliferation, Nutrition, Immunology +21

Roles for insulin-like growth factor-1 in mediating the anti-carcinogenic effects of caloric restriction.

Frank W. Kari, S E Dunn, John E. French et al. · PubMed · 1999 · 88 citations