Efficient Helicene Synthesis: Friedel–Crafts‐type Cyclization of 1,1‐Difluoro‐1‐alkenes

Junji Ichikawa, Misaki Yokota, Takao Kudo, +1

Angewandte Chemie International Edition

DerivativesEngineeringAvailable CompoundsAlkene MetathesisUnique Properties +10

Activation of 1,1-Difluoro-1-alkenes with a Transition-Metal Complex:  Palladium(II)-Catalyzed Friedel–Crafts-Type Cyclization of 4,4-(Difluorohomoallyl)arenes

Misaki Yokota, Daishi Fujita, Junji Ichikawa

Organic Letters

Chemical EngineeringCross-coupling ReactionEngineeringAlkene MetathesisFriedel-crafts-type Cyclization +9

Domino Synthesis of Fluorine‐Substituted Polycyclic Aromatic Hydrocarbons: 1,1‐Difluoroallenes as Synthetic Platforms

Kohei Fuchibe, Yuka Mayumi, Nan Zhao, +3

Angewandte Chemie International Edition

Chemical EngineeringEngineeringHeterocyclicDomino SynthesisAlkene Metathesis +11

Domino Friedel–Crafts‐Type Cyclizations of Difluoroalkenes Promoted by the α‐Cation‐Stabilizing Effect of Fluorine: An Efficient Method for Synthesizing Angular PAHs

Kohei Fuchibe, Hideharu Jyono, Masaki Fujiwara, +3

Chemistry - A European Journal

Camphorsulfonic AcidChemical EngineeringDerivativesEngineeringHeterocyclic +12

Efficient Helicene Synthesis: Friedel–Crafts‐type Cyclization of 1,1‐Difluoro‐1‐alkenes

Junji Ichikawa, Misaki Yokota, Takao Kudo, +1

Angewandte Chemie

Bioorganic ChemistryDerivativesBiochemistryHeterocyclicNatural Sciences +9

Friedel−Crafts-Type Cyclization of 2,2-Difluorovinyl Ketones via α-Fluorocarbocations and Its Application in Domino Cyclizations

Junji Ichikawa, M Kaneko, Misaki Yokota, +2

Organic Letters

EngineeringSubstitution-cyclodehydration ProcessOrganic ChemistryChemistryHeterocycle Chemistry +14

Facile Synthesis of 1,1-Difluoroallenes via the Difluorovinylidenation of Aldehydes and Ketones

Misaki Yokota, Kohei Fuchibe, Mikiko Ueda, +2

Organic Letters

Lithium AcetateCarbonyl CompoundsHeterocyclicAlkene MetathesisFacile Synthesis +6

Friedel-Crafts Cyclization of 1,1-Difluoroalk-1-enes: Synthesis of Benzene-Fused Cyclic Ketones via α-Fluorocarbocations

Junji Ichikawa, Hideharu Jyono, Takao Kudo, +2

Synthesis

DerivativesEngineeringNatural SciencesDiversity-oriented SynthesisFluorous Synthesis +9

Indium(III)-Catalyzed Cationic Cyclization of 1,1-Difluoroallenes: Regioselective Synthesis of 1-Fluoronaphthalenes

Kohei Fuchibe, Yuka Mayumi, Misaki Yokota, +2

Bulletin of the Chemical Society of Japan

Chemical EngineeringCross-coupling ReactionEngineeringAlkene MetathesisCationic Cyclization +7

γ-Selective Addition to 1,1-Difluoroallenes: Three-component Coupling Leading to 2,2-Disubstituted 1,1-Difluoroalkenes

Kohei Fuchibe, Mikiko Ueda, Misaki Yokota, +1

Chemistry Letters

2,2-Difluorovinylcopper IntermediatesCross-coupling ReactionEngineeringFluorous SynthesisOrganic Chemistry +7