Tungsten-induced protein aggregation: Solution behavior

Yijia Jiang, Yasser Nashed-Samuel, Cynthia Li, +14

Journal of Pharmaceutical Sciences

Physicochemical AnalysisProtein FoldingTungsten-induced Protein AggregationMolecular AggregateMedicine +1

Root Cause Analysis of Tungsten-Induced Protein Aggregation in Pre-filled Syringes.

Wei Liu, R. M. Swift, Gianni Torraca, +8

PubMed

Root Cause AnalysisChemical EngineeringResidual TungstenResidual Tungsten ContentEngineering +11

Free Fatty Acid Particles in Protein Formulations, Part 1: Microspectroscopic Identification

Xiaolin Cao, R. Matthew Fesinmeyer, Christopher J. Pierini, +5

Journal of Pharmaceutical Sciences

Food ColloidLipid AnalysisPart 1BiochemistryMicrospectroscopic Identification +5

Detection of Trace Melamine in Raw Materials Used for Protein Pharmaceutical Manufacturing Using Surface-Enhanced Raman Spectroscopy (SERS) with Gold Nanoparticles

Zai‐Qing Wen, Guiyang Li, Da Ren

Applied Spectroscopy

EngineeringMetal NanoparticlesFood AnalysisRaw MaterialsSurface-enhanced Raman Scattering +17

Direct Visualization of Protein Adsorption to Primary Containers by Gold Nanoparticles

Bruce Eu, Alex S. Cairns, Grace Ding, +2

Journal of Pharmaceutical Sciences

NanoparticlesEngineeringProtein NanoparticlesMetal NanoparticlesNanomaterials +7

Effect of pH, Temperature, and Salt on the Stability of <i>Escherichia coli-</i> and Chinese Hamster Ovary Cell-Derived IgG1 Fc

Cynthia H. Li, Linda O. Narhi, Jie Wen, +7

Biochemistry

Salt ConcentrationProtein AssemblyBacteriologyCh2 DomainCellular Physiology +15

Conformation and Side Chains Environments of Recombinant Human Interleukin-1 Receptor Antagonist (rh-IL-1ra) Probed by Raman, Raman Optical Activity, and UV-Resonance Raman Spectroscopy

Zai‐Qing Wen, Xiaolin Cao, Aylin Vance

Journal of Pharmaceutical Sciences

Side Chains EnvironmentsMedicineSpectroscopySurface-enhanced Raman ScatteringUv-resonance Raman Spectroscopy +5

Distribution of silicone oil in prefilled glass syringes probed with optical and spectroscopic methods.

Zai‐Qing Wen, Aylin Vance, Fabian Vega, +3

PubMed

Optical MaterialsEngineeringMicroscopyOptical GlassGlass Material +23

Raman Microscopic Applications in the Biopharmaceutical Industry: <i>In situ</i> Identification of Foreign Particulates inside Glass Containers with Aqueous Formulated Solutions

Xiaolin Cao, Zai‐Qing Wen, Aylin Vance, +1

Applied Spectroscopy

EngineeringMicroscopyRaman Microscopic ApplicationsParticle IdentificationAnalytical Microsystems +17

Nondestructive Detection of Glass Vial Inner Surface Morphology with Differential Interference Contrast Microscopy

Zai‐Qing Wen, Gianni Torraca, Peter Masatani, +2

Journal of Pharmaceutical Sciences

EngineeringMicroscope Image ProcessingMicroscopyOptical PropertiesMicroscopy Method +7