Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

Robin Kate Kelley, Makoto Ueno, Changhoon Yoo, +208

The Lancet

UrologySurgical OncologyGastrointestinal OncologyMedicineBiliary Cancer +3

SIRT3/SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress

Jing Gao, Zhihui Feng, Xueqiang Wang, +10

Cell Death and Differentiation

Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

Ke Cao, Jie Xu, Xuan Zou, +10

Free Radical Biology and Medicine

ObesityMetabolic SyndromeMitochondrial AbnormalitiesOxysterolMetabolic Disorder +10

Mitochondrial Dysfunction in Obesity-Associated Nonalcoholic Fatty Liver Disease: The Protective Effects of Pomegranate with Its Active Component Punicalagin

Xuan Zou, Chunhong Yan, Yujie Shi, +23

Antioxidants and Redox Signaling

Fabricating MnO₂ Nanozymes as Intracellular Catalytic DNA Circuit Generators for Versatile Imaging of Base‐Excision Repair in Living Cells

Feng Chen, Min Bai, Ke Cao, +1

Advanced Functional Materials

Conformation FoldingEngineeringBiomolecular ToolBiological ProcessesMolecular Biology +22

Mitochondrial Dysfunction Launches Dexamethasone-Induced Skeletal Muscle Atrophy via AMPK/FOXO3 Signaling

Jing Liu, Yunhua Peng, Xun Wang, +8

Molecular Pharmaceutics

Mitochondrial MyopathyMitophagyMitochondrial BiogenesisMitochondrial FunctionBiochemistry +12

Programming Enzyme-Initiated Autonomous DNAzyme Nanodevices in Living Cells

Feng Chen, Min Bai, Ke Cao, +8

ACS Nano

Hydroxytyrosol improves mitochondrial function and reduces oxidative stress in the brain of<i>db/db</i>mice: role of AMP-activated protein kinase activation

Adi Zheng, Hao Li, Jie Xu, +8

British Journal Of Nutrition

Maternal hydroxytyrosol administration improves neurogenesis and cognitive function in prenatally stressed offspring

Adi Zheng, Hao Li, Ke Cao, +6

The Journal of Nutritional Biochemistry

Developmental BiologyStress HormoneMaternal Hydroxytyrosol AdministrationBrain DevelopmentDevelopmental Toxicology +8

AMPK activation prevents prenatal stress-induced cognitive impairment: Modulation of mitochondrial content and oxidative stress

Ke Cao, Adi Zheng, Jie Xu, +9

Free Radical Biology and Medicine

Reductive StressMitochondrial ContentPhysiologyNeuroprotectionNeuroscience +3