BMDExpress 2: enhanced transcriptomic dose-response analysis workflow

Jason Phillips, Daniel Svoboda, Arpit Tandon, +16

Bioinformatics

Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment

Reza Farmahin, Andrew Williams, Byron Kuo, +7

Archives of Toxicology

A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells

Asim Siddiqui, Jaswinder Khattra, Allen Delaney, +47

Proceedings of the National Academy of Sciences

High-Throughput Transcriptomic Analysis of Human Primary Hepatocyte Spheroids Exposed to Per- and Polyfluoroalkyl Substances as a Platform for Relative Potency Characterization

Andrea Rowan‐Carroll, Anthony Reardon, Karen Leingartner, +12

Toxicological Sciences

Potency Ranking of Per- and Polyfluoroalkyl Substances Using High-Throughput Transcriptomic Analysis of Human Liver Spheroids

Anthony Reardon, Andrea Rowan‐Carroll, Stephen Ferguson, +10

Toxicological Sciences

Metabolomic ProfilingGene Expression ChangesPotency RankingBioanalysisIncreased Transcriptional Potency +23

Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage

Sabina Halappanavar, Dongmei Wu, Andrew Williams, +4

Toxicology

Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats

Hongyan Dong, Santokh Gill, Ivan Curran, +4

Archives of Toxicology

Gene expression profiling to identify potentially relevant disease outcomes and support human health risk assessment for carbon black nanoparticle exposure

Julie A. Bourdon, Andrew Williams, Byron Kuo, +6

Toxicology

Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD)

A. Francina Webster, Nikolai L. Chepelev, Rémi Gagné, +4

PLoS ONE

Statistical FilteringEngineeringConservative Bmd ValuesGene Expression ProfilingBioanalysis +20

Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application

Byron Kuo, Marc A. Beal, John W. Wills, +6

Archives of Toxicology