Hypoxia Requires Notch Signaling to Maintain the Undifferentiated Cell State

Maria Gustafsson, Xiaowei Zheng, Teresa Pereira, +7

Developmental Cell

Developmental BiologySignal TransductionRedox RegulatorPhysiologyHypoxia (Medicine) +6

Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype

Linda Holmquist Mengelbier, Erik Fredlund, Tobias Löfstedt, +9

Cancer Cell

Common Target GenesCancer Cell BiologyTumor SuppressorCancer GeneticsSystems Biology +5

Functional Interference between Hypoxia and Dioxin Signal Transduction Pathways: Competition for Recruitment of the Arnt Transcription Factor

Katarina Gradin, Jacqueline McGuire, Roland H. Wenger, +6

Molecular and Cellular Biology

Molecular BiologyRedox BiologyOxidative StressRedox RegulatorCell Signaling +15

Activation of hypoxia-inducible factor 1α: Posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

Pekka Kallio, Ingemar Pongratz, Katarina Gradin, +2

Proceedings of the National Academy of Sciences

A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors

Patrik Andersson, Jacqueline McGuire, Carlos Rubio-Terrés, +5

Proceedings of the National Academy of Sciences

Gastrointestinal Peptide HormoneBiochemistryGastrointestinal OncologyMedicineOncogenic Agent +11

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

Xiaofeng Zheng, Sarah Linke, José M. Dias, +16

Proceedings of the National Academy of Sciences

Hif-1 DefinesAdditional ModeNotch IcdSignaling PathwaysRedox Biology +18

Structure and Expression of the Ah Receptor Repressor Gene

Takashi Baba, Junsei Mimura, Katarina Gradin, +6

Journal of Biological Chemistry

Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response

Adam T. Boutin, Alexander Weidemann, Zhenxing Fu, +13

Cell

InflammationPhysiologyExtracellular MatrixHypoxia (Medicine)Tissue Oxygenation +9

HIF1α delays premature senescence through the activation of MIF

Scott M. Welford, Barbara Bedogni, Katarina Gradin, +3

Genes & Development

Cross-coupling of signal transduction pathways: the dioxin receptor mediates induction of cytochrome P-450IA1 expression via a protein kinase C-dependent mechanism.

Anna Berghard, Katarina Gradin, Ingemar Pongratz, +2

Molecular and Cellular Biology

Signal Transduction PathwaysMolecular BiologyRedox BiologyOxidative StressMolecular Pharmacology +18