Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice

Jun‐Li Liu, Karen T. Coschigano, Katie Robertson, +5

American Journal of Physiology-Endocrinology and Metabolism

ObesityMetabolic SyndromeInsulin SensitivityGrowth Hormone SignalingSignal Transduction +13

Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression

Yubin Guo, Qing Ye, Pan Deng, +11

Nature Communications

Pancreatic-Specific Inactivation of IGF-I Gene Causes Enlarged Pancreatic Islets and Significant Resistance to Diabetes

Yarong Lu, Pedro L. Herrera, Yubin Guo, +4

Diabetes

Pancreatic-specific InactivationHuman GrowthImmunologyPathologyInsulin Signaling +16

Pancreatic Islet-Specific Expression of an Insulin-Like Growth Factor-I Transgene Compensates Islet Cell Growth in Growth Hormone Receptor Gene-Deficient Mice

Yubin Guo, Yarong Lu, Daniel Houle, +5

Endocrinology

Abstract LB-125: Snail determines the efficacy of mTOR-targeted therapies by transcriptional repression of 4E-BP1

Jun Wang, Qing Ye, Yubin Guo, +7

Cancer Research

Molecular RegulationCancer BiologyTranscriptional RepressionTumor BiologyTranscriptional Regulation +16

Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice

Maryam Moussavi, Ladan Fazli, Howard Tearle, +6

Cancer Research

Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer

Miriam Butler, Mani Roshan‐Moniri, Michael Hsing, +19

Oncotarget

Dna BindingNatural SciencesErg Protein VariantsSmall MoleculesReceptor Tyrosine Kinase +12

Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects

Qing Ye, Yinan Zhang, Yanan Cao, +14

Cell chemical biology

Glutaredoxin 3MedicineLipid PeroxidationCell DeathTumor Suppressor +6

Osteoclast precursors acquire sensitivity to breast cancer derived factors early in differentiation

Yubin Guo, Kerstin Tiedemann, Jad Abou Khalil, +3

Bone

Cancer ResearchBreast OncologyDevelopmental BiologyBone Morphogenic ProteinBreast Cancer +6

Breast Cancer-derived Factors Stimulate Osteoclastogenesis through the Ca2+/Protein Kinase C and Transforming Growth Factor-β/MAPK Signaling Pathways

Kerstin Tiedemann, Osama Hussein, Gulzhakhan Sadvakassova, +3

Journal of Biological Chemistry