Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy

Zigao Yuan, Shaopeng Chen, Qinsheng Sun, +6

Bioorganic & Medicinal Chemistry

Cancer TherapyMedicinal ChemistryHdac InhibitorsOncologyDual Parp +8

Novel synthetic acridine derivatives as potent DNA-binding and apoptosis-inducing antitumor agents

Xuliang Lang, Lulu Li, Qinsheng Sun, +6

Bioorganic & Medicinal Chemistry

Medicinal ChemistryMedicineCell DeathPharmacological AgentAnti-cancer Agent +5

Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents

Chunmei Gao, Bin Li, Bin Zhang, +7

Bioorganic & Medicinal Chemistry

Medicinal ChemistryPotential Dna-bindingBiochemistryAntiparasitic AgentNatural Sciences +10

Exploration of acridine scaffold as a potentially interesting scaffold for discovering novel multi-target VEGFR-2 and Src kinase inhibitors

Xudong Luan, Chunmei Gao, Nannan Zhang, +5

Bioorganic & Medicinal Chemistry

Medicinal ChemistryDrug TargetAcridine ScaffoldNatural SciencesMedicine +9

Branched rolling circle amplification method for measuring serum circulating micro<scp>RNA</scp> levels for early breast cancer detection

Tingting Fan, Yu Mao, Qinsheng Sun, +5

Cancer Science

Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors

Zigao Yuan, Qinsheng Sun, Dan Li, +6

European Journal of Medicinal Chemistry

Medicinal ChemistryHdac InhibitorsPharmaceutical ScienceChemoprevention StrategyMedicine +8

Development of a versatile DNMT and HDAC inhibitor C02S modulating multiple cancer hallmarks for breast cancer therapy

Zigao Yuan, Shaopeng Chen, Chunmei Gao, +6

Bioorganic Chemistry

Breast OncologyMedicineBreast Cancer TherapyBreast CancerAnti-cancer Agent +7

New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway

Kang Chen, Bizhu Chu, Feng Liu, +6

Acta Pharmacologica Sinica

Oncogenic AgentMedicineApoptosisCell DeathAnti-cancer Agent +5

microRNA 21‐mediated suppression of sprouty1 by Pokemon affects liver cancer cell growth and proliferation

Xiu‐Li Jin, Qinsheng Sun, Feng Liu, +5

Journal of Cellular Biochemistry

Antiproliferative activities of the second-generation antipsychotic drug sertindole against breast cancers with a potential application for treatment of breast-to-brain metastases

Wei Zhang, Cunlong Zhang, Feng Liu, +8

Scientific Reports