Comprehensive pharmacokinetics of a humanized antibody and analysis of residual anti-idiotypic responses.

Sue Stephens, Spencer Emtage, Olivia M. Vetterlein, +7

PubMed

ImmunologyImmunoeditingPathologyImmunophenotypingPharmacotherapy +15

The N-terminal end of the CH2 domain of chimeric human IgG1 anti-HLA-DR is necessary for C1q, Fc gamma RI and Fc gamma RIII binding.

A Morgan, Nick D. Jones, Andrew Nesbitt, +3

PubMed

HistocompatibilityHlaHla ImmunogeneticsImmunologyCh2 Domain +19

The in vivo release of 90Y from cyclic and acyclic ligand-antibody conjugates

A. Harrison, Carole A. Walker, David Parker, +15

International Journal of Radiation Applications and Instrumentation Part B Nuclear Medicine and Biology

Acyclic Ligand-antibody ConjugatesMedicineImmunologyAntibody ScreeningVivo Release +4

Differential effect of isotype on efficacy of anti-tumor necrosis factor alpha chimeric antibodies in experimental septic shock.

Amanda Suitters, Roly Foulkes, Steven M. Opal, +7

The Journal of Experimental Medicine

Preparation, characterisation and tumour targeting of cross-linked divalent and trivalent anti-tumour Fab' fragments

JL Casey, DJ King, L Chaplin, +5

British Journal of Cancer

NanomedicineEngineeringPolymer-drug ConjugateBioconjugationCross-linked Divalent +9

Tumour targeting of humanised cross-linked divalent-fab′ antibody fragments: a clinical phase I/II study

Joanne L. Casey, Mark Napier, David J. King, +8

British Journal of Cancer

Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin

Julia Hubbard, S.R. Martin, L Chaplin, +3

Biochemical Journal

Protein ChemistryProteinlipid InteractionCalcitonin-gene-related PeptideHistidine IonizationProtein Assembly +11

Hydrophobic interaction fast protein liquid chromatography of milk proteins

L Chaplin

Journal of Chromatography A

Protein ChemistryBiochemistryBioanalysisMedicineHydrophobic Interaction +2

Role of TNF alpha in the induction of antigen induced arthritis in the rabbit and the anti-arthritic effect of species specific TNF alpha neutralising monoclonal antibodies.

J Lewthwaite, Simon Blake, Tim Hardingham, +7

Annals of the Rheumatic Diseases

Reserpic acid as an inhibitor of norepinephrine transport into chromaffin vesicle ghosts.

L Chaplin, Adi Cohen, Peter Huettl, +3

Journal of Biological Chemistry

Protein SecretionChromaffin Vesicle GhostsPharmacotherapyChemical BiologyCellular Physiology +18