Hans-Juergen Mest

The Novel Imidazoline Compound BL11282 Potentiates Glucose-Induced Insulin Secretion in Pancreatic β-Cells in the Absence of Modulation of KATP Channel Activity

Alexander M. Efanov, Hans-Juergen Mest, Achim Raap et al. · Diabetes · 2001 · 61 citations · Full text

Different Modes of Action of the Imidazoline Compound RX871024 in Pancreatic β‐Cells: Blocking of K⁺ Channels, Mobilization of Ca²⁺ from Endoplasmic Reticulum, and Interaction with Exocytotic Machinery^a

S. V. Zaitsev, Alexander M. Efanov, Achim Raap et al. · Annals of the New York Academy of Sciences · 1999 · 21 citations

Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site

Scott M. Sheehan, Hans-Juergen Mest, Brian M. Watson et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 19 citations · Full text

Molecular Docking, Biochemistry, Medicine +7

Dipeptidyl peptidase-IV inhibitors can restore glucose homeostasis in type 2 diabetics via incretin enhancement.

Hans-Juergen Mest · PubMed · 2006 · 18 citations

Obesity, Metabolic Syndrome, Diabetes Management +15

Insulinotropic activity of the imidazoline derivative RX871024 in the diabetic GK rat

Alexander M. Efanov, Ioulia B. Appelskog, Samy M. Abdel‐Halim et al. · American Journal of Physiology-Endocrinology and Metabolism · 2002 · 13 citations