Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallography

Motoyasu Adachi, Takashi Ohhara, Kazuo Kurihara, +16

Proceedings of the National Academy of Sciences

Design and synthesis of Rho kinase inhibitors (I)

Atsuya Takami, Masayuki Iwakubo, Yuji Okada, +12

Bioorganic & Medicinal Chemistry

Medicinal ChemistryMedicineRational Drug DesignPharmacologyRho Kinase Inhibitors +1

Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to Vα14 NKT cells

Noriaki Kamada, Hiroshi Iijima, Kaname Kimura, +9

International Immunology

Protein kinase C modulators bearing dicarba-closo-dodecaborane as a hydrophobic pharmacophore

Yasuyuki Endo, Tomohiro Yoshimi, Kaname Kimura, +1

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBiochemistryNatural SciencesMedicine +5

Orally active anti-proliferation agents: novel diphenylamine derivatives as FGF-R2 autophosphorylation inhibitors

Toshiyuki Shimizu, Yasunari Fujiwara, Tatsushi Osawa, +11

Bioorganic & Medicinal Chemistry Letters

Fgf-r2 Autophosphorylation InhibitorsNovel Diphenylamine DerivativesMedicineFibroblast Growth FactorPharmacotherapy +6

Extensive Survey of Antibody Invariant Positions for Efficient Chemical Conjugation Using Expanded Genetic Codes

Akifumi Kato, M. Kuratani, T. Yanagisawa, +7

Bioconjugate Chemistry

Structure–activity relationship and conformational analysis of monoglycosylceramides on the syngeneic mixed leukocyte reaction

Hiroshi Iijima, Kaname Kimura, Teruyuki Sakai, +5

Bioorganic & Medicinal Chemistry

Structure–activity RelationshipBiochemistryMedicineGlycobiologyAmphiphilic System +5

Synthesis of AB Ring Model System of Taxol <i>via</i> Allylation of 8-Membered Ring Compound and Intramolecular Aldol Condensation

Teruaki Mukaiyama, Isamu Shiina, Kaname Kimura, +2

Chemistry Letters

Ketone 6BEngineeringBiochemistryNatural SciencesIntramolecular Aldol Condensation +10

Docking Study of Bryostatins to Protein Kinase C.DELTA. Cys2 Domain.

Kaname Kimura, Miho Mizutani, Nobuo Tomioka, +3

Chemical and Pharmaceutical Bulletin

Crystal StructureProtein AssemblyBiomolecular Structure PredictionMolecular BiologyProtein Kinase C.delta +18

Synthesis, computer modeling and biological evaluation of novel protein kinase C agonists based on a 7-membered lactam moiety

Yasuyuki Endo, Masako Shimazu, Hiroshi Fukasawa, +5

Bioorganic & Medicinal Chemistry Letters

Combinatorial Chemistry7-Membered Lactam MoietyDrug TargetBioorganic ChemistryBiochemistry +8