Unique binding pocket for KW-4679 in the histamine H1 receptor

Hiromi Nonaka, Shizuo Otaki, Etsuo Ohshima, +5

European Journal of Pharmacology

Drug TargetMolecular PhysiologySignal TransductionBiochemistryG Protein-coupled Receptor +8

Synthesis and antiallergic activity of 11-(aminoalkylidene)-6,11-dihydrodibenz[b,e]oxepin derivatives

Etsuo Ohshima, Shizuo Otaki, Hideyuki Sato, +6

Journal of Medicinal Chemistry

Studies on organic fluorine compounds. XXXIX. Studies on steroids. LXXIX. Synthesis of 1.ALPHA.,25-dihydroxy-26,26,26,27,27,27-hexafluorovitamin D3.

Yoshiro Kobayashi, Takeo Taguchi, Satoshi Mitsuhashi, +3

Chemical and Pharmaceutical Bulletin

Bioorganic Chemistry25-Dihydroxyhexafluorovitamin D3Organic ChemistryChemistryVitamin D Form +14

Endogenously released DOPA is a causal factor for glutamate release and resultant delayed neuronal cell death by transient ischemia in rat striata

Nobuya Furukawa, Nobutaka Arai, Yoshio Goshima, +5

Journal of Neurochemistry

l-DOPA Cyclohexyl Ester Is a Novel Potent and Relatively Stable Competitive Antagonist Against l-DOPA Among Several l-DOPA Ester Compounds

Nobuya Furukawa, Yoshio Goshima, Takeaki Miyamae, +7

The Japanese Journal of Pharmacology

Some interactions of L-DOPA and its related compounds with glutamate receptors

Takeaki Miyamae, Yoshio Goshima, Minako Shimizu, +5

Life Sciences

BiochemistryFunctional SelectivityMedicineNeurotransmitterMechanism Of Action +8

Correlation between emetic effect of phosphodiesterase 4 inhibitors and their occupation of the high-affinity rolipram binding site in Suncus murinus brain

Ryo Hirose, Haruhiko Manabe, Hiromi Nonaka, +5

European Journal of Pharmacology

Signal TransductionSuncus Murinus BrainBiochemistryEmetic EffectMedicine +9

Synthesis and biological activity of 1.ALPHA.-fluoro-25-hydroxyvitamin D3.

Etsuo Ohshima, Hiroshi Sai, Suguru Takatsuto, +4

Chemical and Pharmaceutical Bulletin

1.Alpha.-fluoro-25-hydroxyvitamin D3Bioorganic ChemistryBiochemistryGastrointestinal PharmacologyNatural Sciences +9

L-DOPA Cyclohexyl Ester Is a Novel Stable and Potent Competitive Antagonist Against L-DOPA, as Compared to L-DOPA Methyl Ester

Yoshimi Misu, Yoshio Goshima, Takeaki Miyamae, +6

The Japanese Journal of Pharmacology

PharmacotherapyL-dopa Cyclohexyl EsterExperimental PharmacologyDrug ResistanceMolecular Pharmacology +15

Inhibitory Effect of the 4-Aminotetrahydroquinoline Derivatives, Selective Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cell Antagonists, on Eosinophil Migration Induced by Prostaglandin D2

Hideki Mimura, Toshihide Ikemura, Osamu Kotera, +8

Journal of Pharmacology and Experimental Therapeutics