The Role of Adenosine A2a Receptors in Regulating Gabaergic Synaptic Transmission in Striatal Medium Spiny Neurons

Akihisa Mori, Tomomi Shindou, Michio Ichimura, +2

Advances in behavioral biology

Synaptic PlasticityGabaergic Synaptic TransmissionNeurophysiologySynaptic TransmissionPhysiology +8

The role of adenosine A2a receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons

Akihisa Mori, Tomomi Shindou, M. Ichimura, +2

Journal of Neuroscience

(E)-1,3-Dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists

Junichi Shimada, Fumio Suzuki, Hiromi Nonaka, +2

Journal of Medicinal Chemistry

Altmetric Attention ScorePharmacotherapySystem PharmacologyChemical BiologyPharmaceutical Chemistry +16

Adenosine A2A antagonists with potent anti-cataleptic activity

Junichi Shimada, Nobuaki Koike, Hiromi Nonaka, +8

Bioorganic & Medicinal Chemistry Letters

MedicineAdenosine A2aPharmacotherapyAnesthesiaPharmacology +2

Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure

Fumio Suzuki, Junichi Shimada, Hideaki Mizumoto, +5

Journal of Medicinal Chemistry

KF17837 ((E)-8-(3,4-dimethoxystyryl)-1,3-dipropyl-7-methylxanthine) a potent and selective adenosine A2 receptor antagonist

Hiromi Nonaka, Michio Ichimura, Masami Takeda, +5

European Journal of Pharmacology Molecular Pharmacology

Molecular PharmacologyBiochemistryFunctional SelectivityMedicineMechanism Of Action +5

Adenosine A1 antagonists. 3. Structure-activity relationships on amelioration against scopolamine- or N6-[(R)-phenylisopropyl]adenosine-induced cognitive disturbance

Fumio Suzuki, Junichi Shimada, Shizuo Shiozaki, +6

Journal of Medicinal Chemistry

Molecular PharmacologyAdenosine A1 AntagonistsNeuropeptidesBiochemistryFunctional Selectivity +13

Photoisomerization of a potent and selective adenosine A2 antagonist, (E)-1,3-dipropyl-8-(3,4-dimethoxystyryl)-7-methylxanthine

Yoshiko Nonaka, Junichi Shimada, Hiromi Nonaka, +6

Journal of Medicinal Chemistry

OptogeneticsMolecular PharmacologyMolecular SciencesPharmaceutical ChemistryPhotochromism +13

RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin.

T Tanaka, E. Tsukuda, Mika Nozawa, +5

Molecular Pharmacology

8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors

Junichi Shimada, Fumio Suzuki, Hiromi Nonaka, +1

Journal of Medicinal Chemistry

Medicinal ChemistryA1 Receptor SiteA1-adenosine ReceptorsBiochemistryG Protein-coupled Receptor +10