James C. Bartholomew

Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

L.F. Bjeldanes, Jeong Yoon Kim, Karl R. Grose et al. · Proceedings of the National Academy of Sciences · 1991 · 593 citations

Medicine, Biochemistry, Pharmacology +17

Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication

Qin M. Chen, James C. Bartholomew, Judith Campisi et al. · Biochemical Journal · 1998 · 440 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase

Tory M. Hagen, David Yowe, James C. Bartholomew et al. · Proceedings of the National Academy of Sciences · 1997 · 436 citations

Life Sciences, Cell Biology, Physiology +17

Feeding acetyl- <scp>l</scp> -carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

Tory M. Hagen, Jiankang Liu, Jens Lykkesfeldt et al. · Proceedings of the National Academy of Sciences · 2002 · 312 citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +15

( <i>R</i> )‐α‐Lipoic acid‐supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate

Tory M. Hagen, Russell T. Ingersoll, Jens Lykkesfeldt et al. · The FASEB Journal · 1999 · 290 citations

Life Sciences, Nutrition, Nutritional Sciences +17