Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques

Thomas Lehner, Yufei Wang, Martin Cranage, +11

Nature Medicine

Heat shock proteins generate β-chemokines which function as innate adjuvants enhancing adaptive immunity

Thomas Lehner, Lesley A. Bergmeier, Yufei Wang, +4

European Journal of Immunology

Induction of Mucosal and Systemic Immunity to a Recombinant Simian Immunodeficiency Viral Protein

Thomas Lehner, Lesley A. Bergmeier, C Panagiotidi, +9

Science

Allo-immunization elicits CD8+ T cell-derived chemokines, HIV suppressor factors and resistance to HIV infection in women

Yufei Wang, Louisa Tao, Elaine Mitchell, +6

Nature Medicine

Autoimmune DiseaseHuman RetrovirusImmunologyHiv InfectionImmunodominance +6

Targeted lymph node immunization with simian immunodeficiency virus p27 antigen to elicit genital, rectal, and urinary immune responses in nonhuman primates.

Thomas Lehner, Lesley A. Bergmeier, Louisa Tao, +7

The Journal of Immunology

Rsiv Gag P27Humoral ResponseImmunologyImmunodominancePathology +19

Generation of CD8 suppressor factor and β chemokines, induced by xenogeneic immunization, in the prevention of simian immunodeficiency virus infection in macaques

Yufei Wang, Louisa Tao, Elaine Mitchell, +7

Proceedings of the National Academy of Sciences

ImmunodeficienciesImmunologyXenogeneic ImmunizationImmunodominanceCd8 Suppressor Factor +15

Mucosal model of genital immunization in male rhesus macaques with a recombinant simian immunodeficiency virus p27 antigen

Thomas Lehner, Louisa Tao, C Panagiotidi, +7

Journal of Virology

Primary ImmunodeficiencyMucosal ModelSexual HealthMucosal VaccinationHuman Immunodeficiency Virus +13

T- and B-cell functions and epitope expression in nonhuman primates immunized with simian immunodeficiency virus antigen by the rectal route.

Thomas Lehner, Roger H. Brookes, C Panagiotidi, +7

Proceedings of the National Academy of Sciences

Adaptive Immune SystemImmunologyAntigen ProcessingNonhuman PrimatesImmune System +15

Up‐regulation of β‐chemokines and down‐modulation of CCR5 co‐receptors inhibit simian immunodeficiency virus transmission in non‐human primates

T Lehner, Y. Wang, Martin Cranage, +9

Immunology

Induction of inhibitory antibodies to the CCR5 chemokine receptor and their complementary role in preventing SIV infection in macaques

Thomas Lehner, Yufei Wang, Carl Doyle, +6

European Journal of Immunology