Torcetrapib Induces Aldosterone and Cortisol Production by an Intracellular Calcium-Mediated Mechanism Independently of Cholesteryl Ester Transfer Protein Inhibition

Xiao Hu, Jessica D. Dietz, Chunsheng Xia, +6

Endocrinology

Discovery of zoniporide: A potent and selective sodium–hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility

Angel Guzmán-Pérez, Ronald T. Wester, Mary C. Allen, +14

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyPharmaceutical ChemistryMedicineChemistryPharmacology +2

A Novel Sodium-Hydrogen Exchanger Isoform-1 Inhibitor, Zoniporide, Reduces Ischemic Myocardial Injury in Vitro and in Vivo

Delvin R. Knight, Andrew H. Smith, D. M. Flynn, +9

Journal of Pharmacology and Experimental Therapeutics

3‘-Aminoadenosine-5‘-uronamides:  Discovery of the First Highly Selective Agonist at the Human Adenosine A ₃ Receptor

Michael P. DeNinno, Hiroko Masamune, Lois K. Chenard, +10

Journal of Medicinal Chemistry

Relative Importance of Adenosine A1and A3Receptors in Mediating Physiological or Pharmacological Protection from Ischemic Myocardial Injury in the Rabbit Heart

Roger J. Hill, Joseph J. Oleynek, William P. Magee, +2

Journal of Molecular and Cellular Cardiology

Cardiac MuscleHeart FailureMolecular PhysiologyCardiogenic ShockCardiovascular Disease +10

Cardioprotective effects of ingliforib, a novel glycogen phosphorylase inhibitor

W. Ross Tracey, Judith L. Treadway, William P. Magee, +11

American Journal of Physiology-Heart and Circulatory Physiology

Heart FailureCardiovascular DiseaseBiochemistryGlycogen StoresMedicine +12

Novel<i>N</i>⁶-substituted adenosine 5′-<i>N</i>-methyluronamides with high selectivity for human adenosine A₃receptors reduce ischemic myocardial injury

W. Ross Tracey, William P. Magee, Joseph J. Oleynek, +4

American Journal of Physiology-Heart and Circulatory Physiology

PharmacotherapyExperimental PharmacologyMolecular PharmacologyMedicinal ChemistryIschemic Myocardial Injury +14

Aldose reductase inhibition alone or combined with an adenosine A₃agonist reduces ischemic myocardial injury

W. Ross Tracey, William P. Magee, Craig A. Ellery, +4

American Journal of Physiology-Heart and Circulatory Physiology

CCR2 receptor blockade alters blood monocyte subpopulations but does not affect atherosclerotic lesions in apoE−/− mice

Robert J. Aiello, Bret D. Perry, Patricia-Ann K. Bourassa, +7

Atherosclerosis

InflammationAtherosclerotic LesionsVascular DiseaseCardiovascular DiseaseCell Signaling +10

Zoniporide: a potent and highly selective inhibitor of human Na+/H+ exchanger-1

Ravi B. Marala, Janice A. Brown, Jimmy Kong, +8

European Journal of Pharmacology

Translational PharmacologyBiochemistryMedicinePhysiologySelective Inhibitor +5