Andrew Mountain

Gemtuzumab Ozogamicin, A Potent and Selective Anti-CD33 Antibody−Calicheamicin Conjugate for Treatment of Acute Myeloid Leukemia

Philip R. Hamann, Lois M. Hinman, Irwin Hollander et al. · Bioconjugate Chemistry · 2001 · 587 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

CpG-island fragments from the HNRPA2B1/CBX3genomic locus reduce silencing and enhance transgene expression from the hCMV promoter/enhancer in mammalian cells

Steven G. Williams, Tracey Mustoe, Tony Mulcahy et al. · BMC Biotechnology · 2005 · 150 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing

Michael Antoniou, Lee Harland, Tracey Mustoe et al. · Genomics · 2003 · 141 citations

Life Sciences, Genetics, Molecular Genetics +13

Virus-Directed Enzyme Prodrug Therapy: Intratumoral Administration of a Replication-Deficient Adenovirus Encoding Nitroreductase to Patients With Resectable Liver Cancer

Daniel H. Palmer, Vivien Mautner, Darius F. Mirza et al. · Journal of Clinical Oncology · 2004 · 132 citations · Full text

Medicine, Oncology, Pharmacology +13

Multimerization behaviour of single chain Fv variants for the tumour-binding antibody B72.3

Dominique Desplancq, David J. King, Alastair D. G. Lawson et al. · Protein Engineering Design and Selection · 1994 · 122 citations

Pharmacy, Immunology, Molecular Biology +14