Shou‐Ih Hu

Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits

Lawrence MacPherson, Erol K. Bayburt, Michael Capparelli et al. · Journal of Medicinal Chemistry · 1997 · 325 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Human HtrA, an Evolutionarily Conserved Serine Protease Identified as a Differentially Expressed Gene Product in Osteoarthritic Cartilage

Shou‐Ih Hu, Marc Carozza, Melissa Klein et al. · Journal of Biological Chemistry · 1998 · 209 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Linked Deficiencies in Extracellular PPi and Osteopontin Mediate Pathologic Calcification Associated With Defective PC-1 and ANK Expression

Kristen Johnson, James W. Goding, Deborah Van Etten et al. · Journal of Bone and Mineral Research · 2003 · 198 citations · Full text

Medicine, Orthopaedic Surgery, Bone Metabolism +16

One of two chondrocyte‐expressed isoforms of cartilage intermediate‐layer protein functions as an insulin‐like growth factor 1 antagonist

Kristen Johnson, David Farley, Shou‐Ih Hu et al. · Arthritis & Rheumatism · 2003 · 75 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Inhibition of interleukin-1?-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitors: Potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic synovial fluid

Vishwas Ganu, Ronald Goldberg, Jane Peppard et al. · Arthritis & Rheumatism · 1998 · 54 citations

Medicine, Immunology, Pathobiology +17