Mark J. Holness

Peroxisome-proliferator-activated receptor-α (PPARα) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin

Mary C. Sugden, Karen Bulmer, Geoffrey F. Gibbons et al. · Biochemical Journal · 2002 · 159 citations · Full text

Life Sciences, Biochemistry, Endocrinology +16

Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression

Mary C. Sugden, Alexandra Kraus, Robert A. Harris et al. · Biochemical Journal · 2000 · 105 citations · Full text

Life Sciences, Biochemistry, Physiology +15

Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone

Mark J. Holness, Karen Bulmer, Nicholas D. Smith et al. · Biochemical Journal · 2003 · 85 citations · Full text

Life Sciences, Biochemistry, Endocrinology +15

Expression and regulation of pyruvate dehydrogenase kinase isoforms in the developing rat heart and in adulthood: role of thyroid hormone status and lipid supply

Mary C. Sugden, Maria L. LANGDOWN, Robert A. Harris et al. · Biochemical Journal · 2000 · 83 citations · Full text

Life Sciences, Biochemistry, Physiology +13

Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity

Jonas Byström, Jessica A. Wray, Mary C. Sugden et al. · PLoS ONE · 2011 · 82 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17