Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor

Carrie R. Willcox, Vincent Pitard, Sonia Netzer, +7

Nature Immunology

ImmunologyTumor ImmunityImmunodominancePathologyImmune Surveillance +11

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

Martin S. Davey, Carrie R. Willcox, Stephen Paul Joyce, +9

Nature Communications

Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing

Mohindar Murugesh Karunakaran, Carrie R. Willcox, Mahboob Salim, +19

Immunity

Molecular ImmunologyVγ9vδ2 TcrSignal TransductionNatural SciencesReceptor (Biochemistry) +8

The human Vδ2+ T-cell compartment comprises distinct innate-like Vγ9+ and adaptive Vγ9- subsets

Martin S. Davey, Carrie R. Willcox, Stuart Hunter, +8

Nature Communications

Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen

Carrie R. Willcox, Pierre Vantourout, Mahboob Salim, +8

Immunity

Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self

Fiyaz Mohammed, Mark Cobbold, Angela L. Zarling, +6

Nature Immunology

HistocompatibilitySignal TransductionAutoimmune DiseaseMhc ClassPeptide Library +11

Detection of antibodies to the SARS-CoV-2 spike glycoprotein in both serum and saliva enhances detection of infection

Sian Faustini, Siân E. Jossi, Marisol Pérez-Toledo, +25

BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules <i>via</i> a Conformational Sensor in Its B30.2 Domain

Mahboob Salim, Timothy J. Knowles, Alfie T. Baker, +12

ACS Chemical Biology

Development of a high‐sensitivity ELISA detecting IgG, IgA and IgM antibodies to the SARS‐CoV‐2 spike glycoprotein in serum and saliva

Sian Faustini, Siân E. Jossi, Marisol Pérez-Toledo, +25

Immunology

Viral DiagnosticsImmunologyViral Structural ProteinImmunotherapyCovid-19 +15

Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1

Carrie R. Willcox, Mahboob Salim, Charlotte R. Begley, +8

Cell Reports

EngineeringBtn3a Igv DomainMicrobial PathogensAdaptive Immune SystemImmunology +21