Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

Frank Dieterle, Frank D. Sistare, Federico Goodsaid, +62

Nature Biotechnology

Translational MedicineUrologyRenal FunctionMedicineKidney Failure +7

The Relation between Baseline HIV Drug Resistance and Response to Antiretroviral Therapy: Re-Analysis of Retrospective and Prospective Studies Using a Standardized Data Analysis Plan

Victor DeGruttola, Lynn P. Dix, Richard T. D’Aquila, +19

Antiviral Therapy

PharmacotherapyAntiviral DrugDrug ResistanceProspective StudiesHuman Retrovirus +17

Robust Statistical Methods for Hit Selection in RNA Interference High-Throughput Screening Experiments

Xiaohua Douglas Zhang, Xiting Cindy Yang, Namjin Chung, +6

Pharmacogenomics

A comprehensive transcript index of the human genome generated using microarrays and computational approaches

Eric E. Schadt, Stephen W. Edwards, Debraj GuhaThakurta, +20

Genome biology

High Resolution Discovery Proteomics Reveals Candidate Disease Progression Markers of Alzheimer’s Disease in Human Cerebrospinal Fluid

Ronald C. Hendrickson, Anita Y. H. Lee, Qinghua Song, +29

PLoS ONE

Human Cerebrospinal FluidNeurochemical BiomarkersProteomic TechnologyAlzheimer's DiseaseHuman Csf +15

Pharmacological and Toxicological Effects of Chronic Porcine Growth Hormone Administration in Dogs

S. Prahalada, Lea G. Stabinski, Howard Y. Chen, +6

Toxicologic Pathology

A Performance Evaluation of Three Drug-Induced Liver Injury Biomarkers in the Rat: Alpha-Glutathione S-Transferase, Arginase 1, and 4-Hydroxyphenyl-Pyruvate Dioxygenase

Wendy J. Bailey, Dan Holder, Hima Patel, +8

Toxicological Sciences

Lipid PeroxidationPathologyAlpha-glutathione S-transferaseOxidative StressMolecular Pharmacology +23

Integrating Experimental and Analytic Approaches to Improve Data Quality in Genome-wide RNAi Screens

Xiaohua Douglas Zhang, Amy S. Espeseth, Eric N. Johnson, +11

SLAS DISCOVERY

Androgens drive divergent responses to salt stress in male versus female rat kidneys

David Gerhold, Ansuman Bagchi, Meiqing Lu, +8

Genomics

Divergent ResponsesUrologyEndocrine MechanismSodium HomeostasisHormonal Receptor +7