H2S Inhibits Hyperglycemia-Induced Intrarenal Renin-Angiotensin System Activation via Attenuation of Reactive Oxygen Species Generation

Hong Xue, Ping Yuan, Jun Ni, +11

PLoS ONE

HypertensionRenal InflammationH2s BiosynthesisCell ProliferationRedox Biology +21

P300-dependent STAT3 acetylation is necessary for angiotensin II-induced pro-fibrotic responses in renal tubular epithelial cells

Jun Ni, Yang Shen, Zhen Wang, +10

Acta Pharmacologica Sinica

InflammationFibrosisMolecular PhysiologySignal TransductionUrology +12

Suppression of XBP1S Mediates High Glucose-Induced Oxidative Stress and Extracellular Matrix Synthesis in Renal Mesangial Cell and Kidney of Diabetic Rats

Decui Shao, Jia Liu, Jun Ni, +8

PLoS ONE

Collagen IvLipid PeroxidationEr StressRedox BiologyOxidative Stress +16

Inhibition of STAT3 acetylation is associated with attenuated renal fibrosis in the obstructed kidney

Jun Ni, Yang Shen, Zhen Wang, +10

Acta Pharmacologica Sinica

Obstructed KidneyRenal PathologyRenal InflammationPathologyOxidative Stress +15

Insulin deficiency induces rat renal mesangial cell dysfunction via activation of IGF-1/IGF-1R pathway

Yali Kong, Yang Shen, Jun Ni, +8

Acta Pharmacologica Sinica

Metabolic SyndromeUrologyRenal FunctionMedicineDiabetes +10

SND p102 promotes extracellular matrix accumulation and cell proliferation in rat glomerular mesangial cells via the AT1R/ERK/Smad3 pathway

Jinlan Xu, Xinxin Gan, Jun Ni, +7

Acta Pharmacologica Sinica

InflammationSignal TransductionMolecular PhysiologySignaling PathwayCell Regulation +11

CHOP mediates XBP1S-induced renal mesangial cell necrosis following high glucose treatment

Decui Shao, Jun Ni, Yang Shen, +6

European Journal of Pharmacology

InflammationUrologyRenal FunctionHigh Glucose TreatmentRenal Pathology +10

Gasdermin D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway

Lisha Ma, Ruiqin Shen, Jie Jiao, +6

iScience

Fenretinide inhibits the proliferation and migration of human liver cancer HepG2 cells by downregulating the activation of myosin light chain kinase through the p38‑MAPK signaling pathway

Ling Zhang, Daobin Huang, Decui Shao, +5

Oncology Reports

Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli

Zhen Wang, Jun Ni, Decui Shao, +8

European Journal of Pharmacology

Receptor Up-regulationMolecular PhysiologySignal TransductionIsolated GlomeruliMedicine +8