M.J. Vilarem

Evidence for the Presence of a Functional Pregnane X Receptor Response Element in the CYP3A7 Promoter Gene

Jean‐Marc Pascussi, Youssef Jounaïdi, Lionel Drocourt et al. · Biochemical and Biophysical Research Communications · 1999 · 116 citations

Transcriptional Regulation, Systems Biology, Molecular Physiology +9

The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor

Cécile Calleja, Jean‐Marc Pascussi, J. C. Mani et al. · Nature Medicine · 1998 · 110 citations

Health Sciences, Antibiotics, Medicine +13

Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes.

Lionel Drocourt, Jean‐Marc Pascussi, Eric Assénat et al. · PubMed · 2001 · 105 citations

Calcium Channel Modulators, Cytochromes P450, Cellular Pharmacology +18

Dexamethasone-Mediated Up-Regulation of Human CYP2A6 Involves the Glucocorticoid Receptor and Increased Binding of Hepatic Nuclear Factor 4α to the Proximal Promoter

Tania Onica, Kathleen D. Nichols, Meghan Larin et al. · Molecular Pharmacology · 2007 · 85 citations

Sequence of the 5′-Flanking Region of CYP3A5: Comparative Analysis with CYP3A4 and CYP3A7

Youssef Jounaïdi, Philip S. Guzelian, Patrick Maurel et al. · Biochemical and Biophysical Research Communications · 1994 · 54 citations

Biology, Natural Sciences, Genetics +5