Patrick Maurel

Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.

Lydiane Pichard, Isabelle Fabre, Gérard Fabre et al. · Drug Metabolism and Disposition · 1990 · 437 citations

Medicine, Pharmacology, Toxicology +17

Dexamethasone Induces Pregnane X Receptor and Retinoid X Receptor-α Expression in Human Hepatocytes: Synergistic Increase of CYP3A4 Induction by Pregnane X Receptor Activators

Jean‐Marc Pascussi, Lionel Drocourt, Jean‐Michel Fabre et al. · Molecular Pharmacology · 2000 · 367 citations

Life Sciences, Molecular Biology, Pharmacology +11

Expression of CYP3A4, CYP2B6, andCYP2C9 Is Regulated by the Vitamin D Receptor Pathway in Primary Human Hepatocytes

Lionel Drocourt, Jean-Claude Ourlin, Jean‐Marc Pascussi et al. · Journal of Biological Chemistry · 2002 · 353 citations · Full text

Medicine, Biochemistry, Pharmacology +14

The increase in urinary excretion of 6 beta‐hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction.

Cécile Ged, JM Rouillon, Lydiane Pichard et al. · British Journal of Clinical Pharmacology · 1989 · 332 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Identification of an inducible form of cytochrome P-450 in human liver.

Paul B. Watkins, Steven Wrighton, Patrick Maurel et al. · Proceedings of the National Academy of Sciences · 1985 · 323 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +15