Targeting the NF-κB signaling pathway in Notch1-induced T-cell leukemia

Tomas Vilimas, Joaquina Mascarenhas, Teresa Palomero, +11

Nature Medicine

Notch1-induced T-cell LeukemiaImmune Cell DevelopmentT-regulatory CellImmunologyTumor Immunity +3

Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling

Michael P. Seiler, Rebecca Mathew, Megan K. Liszewski, +5

Nature Immunology

Transcriptional RegulationSignal TransductionSignaling PathwayLymphocyte DevelopmentTranscription Factors Egr1 +6

PLZF induces an intravascular surveillance program mediated by long-lived LFA-1–ICAM-1 interactions

Seddon Y. Thomas, Seth Thomas Scanlon, Klaus Griewank, +6

The Journal of Experimental Medicine

Apoptotic Cells, at All Stages of the Death Process, Trigger Characteristic Signaling Events That Are Divergent from and Dominant over Those Triggered by Necrotic Cells

Vimal Patel, Angelika Longacre, Kevin Hsiao, +6

Journal of Biological Chemistry

ApoptosisImmunologyCell DeathApoptotic CellsInflammation +20

The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival

Malay Mandal, Christine Borowski, Teresa Palomero, +12

The Journal of Experimental Medicine

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellApoptosisImmune Regulation +21

Autoreactive thymic B cells are efficient antigen-presenting cells of cognate self-antigens for T cell negative selection

Jason Perera, Liping Meng, Fanyong Meng, +1

Proceedings of the National Academy of Sciences

Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus

Abdeljabar El Andaloussi, Stephanie Graves, Fanyong Meng, +3

Nature Immunology

Knockout MouseCell LineageDevelopmental BiologySignal TransductionCell Division +8

Alterations of lung microbiota in a mouse model of LPS-induced lung injury

Valeriy Poroyko, Fanyong Meng, Angelo Y. Meliton, +7

American Journal of Physiology-Lung Cellular and Molecular Physiology

AsthmaAcute Lung InjuryLps-induced Lung InjuryInflammatory Lung DiseaseLung Inflammation +17

Distinct APCs Explain the Cytokine Bias of α-Galactosylceramide Variants In Vivo

Li Bai, Michael G. Constantinides, Seddon Y. Thomas, +6

The Journal of Immunology

Cytokine BiasAdaptive Immune SystemImmunologyImmune RegulationImmunodominance +24

Oxidized phospholipids protect against lung injury and endothelial barrier dysfunction caused by heat-inactivated <i>Staphylococcus aureus</i>

Angelo Y. Meliton, Fanyong Meng, Yufeng Tian, +4

American Journal of Physiology-Lung Cellular and Molecular Physiology

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationLipid PeroxidationImmunology +19