Keiko Sekine

Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function

Yanyan Hao, Keiko Sekine, Atsushi Kawabata et al. · Nature Cell Biology · 2004 · 243 citations

Protein Function, Signal Transduction, Cell Signaling +11

Small Molecules Destabilize cIAP1 by Activating Auto-ubiquitylation

Keiko Sekine, Kohei Takubo, Ryo Kikuchi et al. · Journal of Biological Chemistry · 2008 · 166 citations · Full text

Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis

Kazuteru Fukasawa, Hideji Fujii, Yurika Saitoh et al. · Cancer Letters · 2006 · 140 citations

Inflammation, Aminopeptidase N, Angiogenesis +10

HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells

Keiko Sekine, Yanyan Hao, Yasuyuki Suzuki et al. · Biochemical and Biophysical Research Communications · 2005 · 55 citations

Protein Function, Signal Transduction, Signaling Pathway +10

Augmentation of death ligand‐induced apoptosis by aminopeptidase inhibitors in human solid tumor cell lines

Keiko Sekine, Hideji Fujii, Fuminori Abe et al. · International Journal of Cancer · 2001 · 43 citations · Full text

Apoptosis, Immunology, Cell Death +16