Joseph Brunner

The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold

Anthony L. Gotter, Christopher J. Winrow, Joseph Brunner et al. · BMC Neuroscience · 2013 · 93 citations · Full text

Orexin Receptor Antagonists Differ from Standard Sleep Drugs by Promoting Sleep at Doses That Do Not Disrupt Cognition

Jason M. Uslaner, Spencer J. Tye, Donnie Eddins et al. · Science Translational Medicine · 2013 · 89 citations

Sleep Disorders, Current Treatments, Psychotropic Medication +24

Altered Sleep and Affect in the Neurotensin Receptor 1 Knockout Mouse

Karrie Fitzpatrick, Christopher J. Winrow, Anthony L. Gotter et al. · SLEEP · 2012 · 45 citations · Full text

Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators

Andres D. Ramirez, Anthony L. Gotter, Steven V. Fox et al. · Frontiers in Neuroscience · 2013 · 39 citations · Full text

Pharmacotherapy, Social Sciences, Locomotor Performance +17

Identification of MK-8133: An orexin-2 selective receptor antagonist with favorable development properties

Scott D. Kuduk, Jason W. Skudlarek, Christina N. DiMarco et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 20 citations · Full text

Favorable Development Properties, Functional Selectivity, Medicine +8