Yoshiyuki Okano

Tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency

Haruo Shintaku, Shigeo Kure, Toshihiro Ohura et al. · Zhongguo dangdai erke zazhi · 2005 · 254 citations

Biosynthesis, Biochemical Genetics, Biochemistry +1

Molecular Basis of Phenotypic Heterogeneity in Phenylketonuria

Yoshiyuki Okano, Randy C. Eisensmith, Flemming Güttler et al. · New England Journal of Medicine · 1991 · 237 citations

Neonatal intrahepatic cholestasis caused by citrin deficiency: severe hepatic dysfunction in an infant requiring liver transplantation

Akiko Tamamori, Yoshiyuki Okano, Hajime Ozaki et al. · European Journal of Pediatrics · 2002 · 106 citations

Severe Hepatic Dysfunction, Hepatology, Biliary Tract +12

Long-Term Treatment and Diagnosis of Tetrahydrobiopterin-Responsive Hyperphenylalaninemia with a Mutant Phenylalanine Hydroxylase Gene

Haruo Shintaku, Shigeo Kure, Toshihiro Ohura et al. · Pediatric Research · 2003 · 93 citations · Full text

Biochemistry, Natural Sciences, Inherited Metabolic Disease +4

Experimental evidence that phenylalanine is strongly associated to oxidative stress in adolescents and adults with phenylketonuria

Yoshitami Sanayama, Hironori Nagasaka, Masaki Takayanagi et al. · Molecular Genetics and Metabolism · 2011 · 84 citations

Experimental Evidence, Physiology, Metabolism +2