D. Sriram

Coptisine-induced cell cycle arrest at G2/M phase and reactive oxygen species–dependent mitochondria-mediated apoptosis in non-small-cell lung cancer A549 cells

Poorna Chandra Rao, Sajeli Begum, Mahendra Sahai et al. · Tumor Biology · 2017 · 53 citations · Full text

Anti-HIV Activity Of Some Mannich Bases Of Isatin Derivatives

eya, D. Sriram, Erik De Clercq et al. · Indian Journal of Pharmaceutical Sciences · 1998 · 41 citations

Medicinal Chemistry, Biochemistry, Schiff’s Base +13

Syntheses and biological evaluation of new triazole-spirochromone conjugates as inhibitors of Mycobacterium tuberculosis

M. Muthukrishnan, Mohammad Mujahid, Perumal Yogeeswari et al. · Tetrahedron Letters · 2011 · 32 citations

Pulmonary Tuberculosis, Medicine, Mycobacterium Tuberculosis +10

Energy-Based Pharmacophore and Three-Dimensional Quantitative Structure–Activity Relationship (3D-QSAR) Modeling Combined with Virtual Screening To Identify Novel Small-Molecule Inhibitors of Silent Mating-Type Information Regulation 2 Homologue 1 (SIRT1)

Venkat Koushik Pulla, D. Sriram, Srikant Viswanadha et al. · Journal of Chemical Information and Modeling · 2015 · 28 citations

Crystal Structure, Drug Target, Molecular Biology +21

Structure-based drug design of small molecule SIRT1 modulators to treat cancer and metabolic disorders

Venkat Koushik Pulla, Mallika Alvala, D. Sriram et al. · Journal of Molecular Graphics and Modelling · 2014 · 25 citations

Medicine, Natural Sciences, Structure-based Drug Design +9