A. Leyva

Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouridine in relation to drug-metabolizing enzymes.

Godefridus J. Peters, Emile J. Laurensse, A. Leyva et al. · PubMed · 1986 · 193 citations

Chemoprevention Strategy, Pyrimidine Metabolism, Cellular Pharmacology +22

Measurement of DNA in cultured human cells

A. Leyva, William N. Kelley · Analytical Biochemistry · 1974 · 158 citations

Chromatin, Human Cell, Dna +8

Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia

Rob Pieters, D. R. Huismans, A. Leyva et al. · Cancer Letters · 1988 · 149 citations

Hematological Malignancy, Oncology, Engineering +15

Comparison of the rapid automated MTT-assay with a dye exclusion assay for chemosensitivity testing in childhood leukaemia

Rob Pieters, D. R. Huismans, A. Leyva et al. · British Journal of Cancer · 1989 · 127 citations · Full text

Hematological Malignancy, Oncology, Laboratory Hematology +14

Phase I and pharmacokinetic study of 5-aza-2'-deoxycytidine (NSC 127716) in cancer patients.

C.J. van Groeningen, A. Leyva, A.M.P. O'Brien et al. · PubMed · 1986 · 121 citations

Pharmacokinetic Study, Pharmacotherapy, Cancer Patients +16