A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation.

Ken Taniguchi, M. Wada, Kimitoshi Kohno, +7

PubMed

Decreased Drug AccumulationMolecular BiologyAtp BindingCisplatin-resistant Human HeadCancer Biology +15

Role of the human Y box-binding protein YB-1 in cellular sensitivity to the DNA-damaging agents cisplatin, mitomycin C, and ultraviolet light.

Takefumi Ohga, Kazuhisa Koike, Mayumi Ono, +5

PubMed

Ultraviolet LightInverted Ccaat BoxMolecular RegulationImmunologyY Box-binding Protein +20

Most drugs that reverse multidrug resistance also inhibit photoaffinity labeling of P-glycoprotein by a vinblastine analog.

Shin-ichi Akiyama, Marilyn M. Cornwell, M Kuwano, +2

Molecular Pharmacology

Nuclear expression of the Y-box binding protein, YB-1, as a novel marker of disease progression in non-small cell lung cancer.

Kotaro Shibahara, Kenji Sugio, T Osaki, +6

PubMed

Inverted Ccaat BoxDisease ProgressionPathologyCancer BiologyTumor Biology +14

Akt-dependent nuclear localization of Y-box-binding protein 1 in acquisition of malignant characteristics by human ovarian cancer cells

Y Basaki, Fumihito Hosoi, Yoshinao Oda, +10

Oncogene

Y-box-binding Protein 1MedicineAkt-dependent Nuclear LocalizationMalignant CharacteristicsRadiation Oncology +5

Increased phosphorylation of DNA topoisomerase II in etoposide-resistant mutants of human cancer KB cells.

Hiroshi Takano, Kimitoshi Kohno, Makoto Ono, +2

PubMed

Molecular BiologyPathologyEtoposide-resistant MutantsCancer BiologyTumor Biology +17

Suppression of retinal neovascularization by the NF-kappaB inhibitor pyrrolidine dithiocarbamate in mice.

Ayako Yoshida, Shigeo Yoshida, Tatsuro Ishibashi, +2

PubMed

Basal Membrane Localization of MRP1 in Human Placental Trophoblast

M. Nagashige, Fumihiko Ushigome, Noriko Koyabu, +10

Placenta

Basal Membrane LocalizationDevelopmental BiologyCellular BiochemistryMedicineCell Biology +1

The mechanism for the activation of latent TGF-beta during co-culture of endothelial cells and smooth muscle cells: cell-type specific targeting of latent TGF-beta to smooth muscle cells.

Yasufumi Sato, Futoshi Okada, Mayumi Abé, +6

The Journal of Cell Biology

Endothelial CellsCell ProliferationBiomedical EngineeringCell GrowthCellular Physiology +17

Enhanced coexpression of thioredoxin and high mobility group protein 1 genes in human hepatocellular carcinoma and the possible association with decreased sensitivity to cisplatin.

N. Kawahara, Toshiya Tanaka, Akira Yokomizo, +7

PubMed

Human Hepatocellular CarcinomaPathologyEnhanced CoexpressionCancer BiologyTumor Biology +14