PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

Simona Urbani, Barbara Amadei, D. Tola, +4

Journal of Virology

Hepatitis C VirusImmunologyImmunotherapyInfection IsViral Persistence +14

Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.

Carolina Boni, Antonio Bertoletti, Amalia Penna, +8

Journal of Clinical Investigation

ImmunologyHepatitis BPathologyChronic Hepatitis BImmunotherapy +17

Lamivudine Treatment Can Overcome Cytotoxic T–Cell Hyporesponsiveness in Chronic Hepatitis B: New Perspectives for Immune Therapy

Carolina Boni, Amalia Penna, Graham S. Ogg, +9

Hepatology

CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained

Franziska Lechner, Norbert H. Gruener, Simona Urbani, +8

European Journal of Immunology

Immunological MemoryAutoimmune DiseaseHepatitis CViral HepatitisImmunology +11

Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B

Carolina Boni, Amalia Penna, Antonio Bertoletti, +10

Journal of Hepatology

Transient RestorationHepatologyViral HepatitisLamivudine TherapyImmunology +8

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses

Simona Urbani, Barbara Amadei, Paola Fisicaro, +6

Hepatology

Activation of Natural Killer Cells During Acute Infection With Hepatitis C Virus

Barbara Amadei, Simona Urbani, Angelica Cazaly, +6

Gastroenterology

Host ResponseHepatitis CHepatitis C VirusViral HepatitisImmunology +7

Virus-Specific CD8⁺Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C

Simona Urbani, Carolina Boni, Gabriele Missale, +5

Journal of Virology

Conserved hepatitis C virus sequences are highly immunogenic for CD4+ T cells: Implications for vaccine development

V. Lamonaca, Gabriele Missale, Simona Urbani, +10

Hepatology

VaccinationHcv IsolatesVaccine DevelopmentHepatitis CViral Hepatitis +13

Heterologous T cell immunity in severe hepatitis C virus infection

Simona Urbani, Barbara Amadei, Paola Fisicaro, +4

The Journal of Experimental Medicine