Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection

Carolina Boni, Paola Fisicaro, Caterina Valdatta, +9

Journal of Virology

ImmunologyHepatitis BPathologyT-cell DysfunctionHepatitis B Virus +15

The Role of Virus-Specific Cd8+ Cells in Liver Damage and Viral Control during Persistent Hepatitis B Virus Infection

Mala K. Maini, Carolina Boni, Chun Kyon Lee, +12

The Journal of Experimental Medicine

Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.

Carolina Boni, Antonio Bertoletti, Amalia Penna, +8

Journal of Clinical Investigation

ImmunologyHepatitis BPathologyChronic Hepatitis BImmunotherapy +17

Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection

Mala K. Maini, Carolina Boni, Graham S. Ogg, +10

Gastroenterology

Viral HepatitisImmunologyHepatitis BHepatitisVirology +3

Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues

Carolina Boni, Diletta Laccabue, Pietro Lampertico, +10

Gastroenterology

Ide AnaloguesMedicineT-regulatory CellLong-term Effective TherapyImmunology +7

Lamivudine Treatment Can Overcome Cytotoxic T–Cell Hyporesponsiveness in Chronic Hepatitis B: New Perspectives for Immune Therapy

Carolina Boni, Amalia Penna, Graham S. Ogg, +9

Hepatology

Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B

Paola Fisicaro, Valeria Barili, Barbara Montanini, +14

Nature Medicine

Viral PersistenceHepatologyMitochondrial DysfunctionViral HepatitisAntiviral Activity +7

Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections

Antonio Bertoletti, Mario Milco D’Elios, Carolina Boni, +8

Gastroenterology

Autoimmune DiseaseHepatologyHepatitis CViral HepatitisT-regulatory Cell +11

Early kinetics of innate and adaptive immune responses during hepatitis B virus infection

Paola Fisicaro, Caterina Valdatta, Carolina Boni, +7

Gut

Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B

Carolina Boni, Amalia Penna, Antonio Bertoletti, +10

Journal of Hepatology

Transient RestorationHepatologyViral HepatitisLamivudine TherapyImmunology +8