Sterol Regulatory Element-binding Protein-1 as a Key Transcription Factor for Nutritional Induction of Lipogenic Enzyme Genes

Hitoshi Shimano, Naoya Yahagi, Michiyo Amemiya-Kudo, +10

Journal of Biological Chemistry

Identification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter

Tomohiro Yoshikawa, Hitoshi Shimano, Michiyo Amemiya-Kudo, +13

Molecular and Cellular Biology

Polyunsaturated Fatty Acids Suppress Sterol Regulatory Element-binding Protein 1c Promoter Activity by Inhibition of Liver X Receptor (LXR) Binding to LXR Response Elements

Tomohiro Yoshikawa, Hitoshi Shimano, Naoya Yahagi, +15

Journal of Biological Chemistry

Promoter ActivityPufa SuppressionFatty Liver DiseaseLiver X ReceptorFatty Acids +14

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

Michiyo Amemiya-Kudo, Hitoshi Shimano, Alyssa H. Hasty, +14

Journal of Lipid Research

Absence of Sterol Regulatory Element-binding Protein-1 (SREBP-1) Ameliorates Fatty Livers but Not Obesity or Insulin Resistance in Lep/Lep Mice

Naoya Yahagi, Hitoshi Shimano, Alyssa H. Hasty, +15

Journal of Biological Chemistry

A Crucial Role of Sterol Regulatory Element-binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids

Naoya Yahagi, Hitoshi Shimano, Alyssa H. Hasty, +12

Journal of Biological Chemistry

Fatty Liver DiseaseOxidative StressMetabolic SyndromeTranscriptional RegulationMature Srebp-1 +18

Troglitazone Inhibits Atherosclerosis in Apolipoprotein E–Knockout Mice

Zhong Chen, Shun Ishibashi, Stéphane Perrey, +13

Arteriosclerosis Thrombosis and Vascular Biology

Dual regulation of mouse Δ5- and Δ6-desaturase gene expression by SREBP-1 and PPARα

Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi, +12

Journal of Lipid Research

Promoter Analysis of the Mouse Sterol Regulatory Element-binding Protein-1c Gene

Michiyo Amemiya-Kudo, Hitoshi Shimano, Tomohiro Yoshikawa, +14

Journal of Biological Chemistry

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

Naoya Yahagi, Hitoshi Shimano, Kiyoshi Hasegawa, +16

European Journal of Cancer

HepatologyBiochemistryNatural SciencesLiver PhysiologyLiver Cancer +5