Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase

Reiko Shinkura, Kazuhiro Kitada, Fumihiko Matsuda, +6

Nature Genetics

Nf-κb-inducing KinaseTissue DevelopmentCell RegulationImmune Cell DevelopmentMouse Gene +8

Purification and characterization of a senile amyloid-related antigenic substance (apoSASSAM) from mouse serum. apoSASSAM is an apoA-II apolipoprotein of mouse high density lipoproteins.

Keiichi Higuchi, Tomonori Yonezu, K. Kogishi, +7

Journal of Biological Chemistry

Developmental and age-related changes in apolipoprotein B mRNA editing in mice.

Keiichi Higuchi, Kaori Kitagawa, K. Kogishi, +1

Journal of Lipid Research

Long‐Term Effects of Continual Intake of Phenobarbital on the Spontaneously Epileptic Rat

T. Serikawa, K. Kogishi, Junzo Yamada, +5

Epilepsia

Apolipoprotein A-II gene and development of amyloidosis and senescence in a congenic strain of mice carrying amyloidogenic ApoA-II.

Keiichi Higuchi, Hironobu Naiki, Kaori Kitagawa, +4

PubMed

Age-associated changes in elastin and collagen content and the proportion of types I and III collagen in the lungs of mice

Yukinori Takubo, Toyohiro Hirai, Shigeo Muro, +3

Experimental Gerontology

Developmental BiologyCollagen ContentIii CollagenLongevityPhysiology +5

Amyloid A protein amyloidosis induced in apolipoprotein-E-deficient mice.

Yoshinobu Hoshii, Hiroyuki Kawano, Dan Cui, +6

PubMed

Accelerated Senile Amyloidosis Induced by Amyloidogenic ApoA-II Gene Shortens the Life Span of Mice But Does Not Accelerate the Rate of Senescence

Keiichi Higuchi, Jian Wang, Kakuya Kitagawa, +5

The Journals of Gerontology Series A

Severe Amyloid DepositsAlzheimer's DiseaseAgingLife SpanLongevity +12

A molecular-pathologic approach to murine senile amyloidosis. Serum precursor-apolipoprotein A-II variant (Pro5----Gln) presents only in the senile amyloidosis-prone SAM-P/1 and SAM-P/2 mice.

Tomonori Yonezu, Susumu Tsunasawa, Keiichi Higuchi, +5

PubMed

Lung protein leakage in respiratory failure induced by a hybridoma making monoclonal antibody to the hydrophobic surfactant-associated polypeptide SP-B.

Yasutaka Suzuki, Bengt Robertson, Yoko Fujita, +3

PubMed

Acute Lung InjuryAsthmaInflammatory Lung DiseaseLung InflammationLung Protein Leakage +16