The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of <scp>PGC</scp> ‐1β

Hidetoshi Fujita, Naoko Yagishita, Satoko Aratani, +24

The EMBO Journal

Signal TransductionMitochondrial BiogenesisMitochondrial FunctionE3 Ligase SynoviolinMedicine +6

Abemaciclib induces atypical cell death in cancer cells characterized by formation of cytoplasmic vacuoles derived from lysosomes

Hirotsugu Hino, Noriyoshi Iriyama, Hiroko Kokuba, +6

Cancer Science

Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress-mediated cell death in multiple myeloma cells

Shota Moriya, S Komatsu, Kaho Yamasaki, +8

International Journal of Oncology

MitophagyApoptosisImmunologyCell DeathMacrolide Antibiotics +18

Synthesis of monodispersed molecularly imprinted polymer particles for high-performance liquid chromatographic separation of cholesterol using templating polymerization in porous silica gel bound with cholesterol molecules on its surface

Keiichi Kitahara, Isao Yoshihama, Takako Hanada, +2

Journal of Chromatography A

Polymer ParticlesEngineeringPolymer ScienceMicelleAnalytical Chemistry +5

Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines

Shuntaro Mukai, Shota Moriya, Masaki Hiramoto, +11

International Journal of Oncology

MitophagyApoptosisImmunologyCell DeathCancer Biology +18

Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin

Akihisa Abe, Hiroko Kokuba

Oncology Reports

Azithromycin enhances the cytotoxicity of DNA‐damaging drugs via lysosomal membrane permeabilization in lung cancer cells

Kazutoshi Toriyama, Naoharu Takano, Hiroko Kokuba, +5

Cancer Science

Vitamin K2 induces non-apoptotic cell death along with autophagosome formation in breast cancer cell lines

Shinsuke Miyazawa, Shota Moriya, Hiroko Kokuba, +3

Breast Cancer

Non-apoptotic Cell DeathCell AutophagyMitophagyVitamin K2Apoptosis +11

Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics

Naoharu Takano, Masaki Hiramoto, Yumiko Yamada, +4

British Journal of Cancer

Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines

Kana Miyahara, Hiromi Kazama, Hiroko Kokuba, +9

International Journal of Oncology

Cell DeathMolecular BiologyCytoskeletonEr StressCancer Biology +22