Actively personalized vaccination trial for newly diagnosed glioblastoma

Norbert Hilf, Sabrina Kuttruff-Coqui, Katrin Frenzel, +61

Nature

VaccinationNeuro-oncologyVaccination TrialVaccine TrialTherapeutic Vaccine +4

Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition

Rebecca F. Gottesman, Andrea L.C. Schneider, Yun Zhou, +10

JAMA

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

Lukas Bunse, Stefan Pusch, Theresa Bunse, +51

Nature Medicine

Cancer ImmunosurveillanceMedicineT-regulatory CellImmunologyTumor Immunity +7

A vaccine targeting mutant IDH1 in newly diagnosed glioma

Michael Platten, Lukas Bunse, Antje Wick, +25

Nature

Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas

Mirco Friedrich, Roman Sankowski, Lukas Bunse, +34

Nature Cancer

Effect of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease in The Gambia: a population-based surveillance study

Grant Mackenzie, Philip C. Hill, David Jeffries, +39

The Lancet Infectious Diseases

Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study

Joshua J. Solomon, Sonye K. Danoff, Felix Woodhead, +104

The Lancet Respiratory Medicine

Rheumatoid DisorderRheumatologyPharmacologyClinical TrialsPulmonary Pharmacology +3

The ARIC-PET amyloid imaging study

Rebecca F. Gottesman, Andrea L.C. Schneider, Yun Zhou, +10

Neurology

Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation

Kathrin W. Schulte, Edward Green, Annabel Wilz, +2

Structure

Signal TransductionBiochemistryG Protein-coupled ReceptorNatural SciencesReceptor (Biochemistry) +5

FDXR is a biomarker of radiation exposure in vivo

Gráinne O’Brien, Lourdes Cruz-Garcia, Matthäus Majewski, +24

Scientific Reports