Human Hypertension Caused by Mutations in WNK Kinases

Frederick H. Wilson, Sandra Disse-Nicodème, Keith A. Choate, +16

Science

Hypoadiponectinemia Is an Independent Risk Factor for Hypertension

Yoshio Iwashima, Tomohiro Katsuya, Kazuhiko Ishikawa, +13

Hypertension

Sodium Restriction Shifts Circadian Rhythm of Blood Pressure From Nondipper to Dipper in Essential Hypertension

Takashi Uzu, Kazuhiko Ishikawa, Takashi Fujii, +3

Circulation

Relationship Between Left Ventricular Geometry and Natriuretic Peptide Levels in Essential Hypertension

Toshio Nishikimi, Fumiki Yoshihara, Atsushi Morimoto, +7

Hypertension

HypertensionCardiovascular FunctionDiastolic FunctionBlood PressureNatriuretic Peptide Levels +15

Klotho suppresses TNF-α-induced expression of adhesion molecules in the endothelium and attenuates NF-κB activation

Yoshihiro Maekawa, Kazuhiko Ishikawa, Osamu Yasuda, +7

Endocrine

Cell AdhesionImmunologyImmune RegulationTnf-α-induced ExpressionCellular Physiology +15

Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells

Masashi Ikushima, Hiromi Rakugi, Kazuhiko Ishikawa, +6

Biochemical and Biophysical Research Communications

InflammationEndothelial Cell PathobiologyAngiogenesisAtherosclerosisMedicine +11

Deletion Allele of Angiotensin-Converting Enzyme Gene Increases Risk of Essential Hypertension in Japanese Men

Jitsuo Higaki, Shunroku Baba, Tomohiro Katsuya, +5

Circulation

Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease

Koji Ohashi, Noriyuki Ouchi, Shinji Kihara, +19

Journal of the American College of Cardiology

ObesityMetabolic SyndromeMetabolic DisorderCardiovascular DiseaseMetabolic Disease +10

High Sodium Sensitivity Implicates Nocturnal Hypertension in Essential Hypertension

Takashi Uzu, Frida S. Kazembe, Kazuhiko Ishikawa, +3

Hypertension

NutritionHypertensionElectrolyte DisorderBlood Pressure VariabilityBlood Pressure +14

Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca ²⁺ channel to maintain endothelial integrity

Tetsuro Kusaba, Mitsuhiko Okigaki, Akihiro Matui, +12

Proceedings of the National Academy of Sciences

Klotho DeficiencyImmunologyPathologyCell DeathCellular Physiology +18