J F Gauchat

Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production.

J F Gauchat, Deborah A. Lebman, Robert L. Coffman et al. · The Journal of Experimental Medicine · 1990 · 351 citations

Lymphocyte Development, Adaptive Immune System, Immunology +20

Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones.

Hugues Gascan, J F Gauchat, Maria Grazia Roncarolo et al. · The Journal of Experimental Medicine · 1991 · 331 citations · Full text

B Cell Clones, Lymphocyte Development, Adaptive Immune System +19

Anti-CD40 monoclonal antibodies or CD4+ T cell clones and IL-4 induce IgG4 and IgE switching in purified human B cells via different signaling pathways

Hugues Gascan, J F Gauchat, Gregorio Aversa et al. · The Journal of Immunology · 1991 · 268 citations · Full text

Superoxide-dependent nitroblue tetrazolium reduction and expression of cytochrome <i>b</i>-245 components by human tonsillar B lymphocytes and B cell lines.

F.E. Maly, Michio Nakamura, J F Gauchat et al. · The Journal of Immunology · 1989 · 139 citations

Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis.

Pascale Jeannin, Yves Delneste, Sybille Lecoanet-Henchoz et al. · The Journal of Experimental Medicine · 1995 · 126 citations · Full text

Inflammation, Cytokine, Il-4-induced Immunoglobulin Synthesis +15