Jeffrey Wu

Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies

Daniel Robbins, Mark Noviski, Ying Siow Tan et al. · Journal of Medicinal Chemistry · 2024 · 78 citations · Full text

Design of Annulated Pyrazoles as Inhibitors of HIV-1 Reverse Transcriptase

Zachary K. Sweeney, Seth F. Harris, Nidhi Arora et al. · Journal of Medicinal Chemistry · 2008 · 74 citations · Full text

Reverse Transcriptase Enzyme, Molecular Biology, Cell Culture +17

Nx-2127, a Degrader of BTK and IMiD Neosubstrates, for the Treatment of B-Cell Malignancies

Daniel Robbins, Aileen Kelly, May Tan et al. · Blood · 2020 · 45 citations

Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase

Zachary K. Sweeney, Sahaja Acharya, Andrew J. Briggs et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 29 citations · Full text

Antiviral Compound, Medicine, Antiviral Drug Development +6

Diphenyl Ether Non‐Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties

Zachary K. Sweeney, Joshua J. Kennedy‐Smith, Jeffrey Wu et al. · ChemMedChem · 2008 · 27 citations

Engineering, Viral Polymerase Structure, Viral Polymerase Mechanism +17