P Lipari

Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.

Ming Liu, Matthew Bryant, Jianping Chen et al. · PubMed · 1998 · 309 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer.

Loretta L. Nielsen, P Lipari, J Dell et al. · PubMed · 1998 · 125 citations

Medicine, Oncology, Pharmacology +13

Toxin-Mediated Paracellular Transport of Antitoxin Antibodies Facilitates Protection against Clostridium difficile Infection

Z. Zhang, X. Chen, Lorraine D. Hernandez et al. · Infection and Immunity · 2014 · 44 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice

Ming Liu, Matthew Bryant, Jianping Chen et al. · Cancer Chemotherapy and Pharmacology · 1999 · 43 citations

Medicine, Oncology, Pharmacology +14

Combination therapy with the farnesyl protein transferase inhibitor SCH66336 and SCH58500 (p53 adenovirus) in preclinical cancer models.

Loretta L. Nielsen, Bin Shi, Gerald Hajian et al. · PubMed · 1999 · 36 citations

Medicine, Oncology, Pharmacology +13